Merrill Lynch, Pierce, Fenner & Smith

Incorporated

One Bryant Park

New York, NY 10036

Cowen and Company, LLC

555 California Street, 5th Floor

San Francisco, CA 94104

Leerink Partners, LLC

299 Park Avenue, 21st Floor

New York, NY 10171

 

May 1, 2015

 

Re:                             Adaptimmune Therapeutics plc

Registration Statement on Form F-1

Registration File No. 333-203267

 

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

 

Dear Sir/Madam:

 

Pursuant to Rule 460 of the General Rules and Regulations under the Securities Act of 1933 (the “Act”), we, as representatives of the several Underwriters, wish to advise you that 1,855 copies of the Preliminary Prospectus included in the Registration Statement on Form F-1 were distributed during the period April 27 through the date hereof, to prospective underwriters, institutions, dealers and others.

 

We hereby confirm that we will, and have been informed by the other participating underwriters that they will, comply with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934.

 

In accordance with Rule 461 of the Act, we hereby join in the request of Adaptimmune Therapeutics plc for acceleration of the effective date of the above-named Registration Statement so that it becomes effective at 4:00 p.m. Eastern time on May 5, 2015, or as soon thereafter as practicable.

 

[Remainder of page intentionally left blank]

 



 

 

Very truly yours,

 

 

 

 

By:

MERRILL LYNCH, PIERCE, FENNER & SMITH
INCORPORATED

 

 

 

 

By:

/s/ Michael Liloia

 

 

Name: Michael Liloia

 

 

Title: Vice-President

 

 

 

 

By:

COWEN AND COMPANY, LLC

 

 

 

 

By:

/s/ Christopher Weekes

 

 

Name: Christopher Weekes

 

 

Title: Managing Director

 

 

 

 

By:

LEERINK PARTNERS, LLC

 

 

 

 

By:

/s/ John I. Fitzgerald, Esq.

 

 

Name: John I. Fitzgerald, Esq.

 

 

Title: Managing Director

 

[Signature page to Acceleration Request Letter]