Quarterly report pursuant to Section 13 or 15(d)

CONDENSED CONSOLIDATED STATEMENT OF CHANGE IN EQUITY

v3.10.0.1
CONDENSED CONSOLIDATED STATEMENT OF CHANGE IN EQUITY - USD ($)
$ in Thousands
Common stock
Additional paid in capital
Accumulated foreign currency translation adjustments
Accumulated unrealized gains (losses) on available-for-sale debt securities
Accumulated deficit
Total
Increase (Decrease) in Stockholders' Equity            
Cumulative effect of applying new accounting standards         $ 8,645 $ 8,645
Beginning balance as adjusted $ 854 $ 455,401 $ (17,867) $ (3,774) (222,985) 211,629
Balance at the beginning of the period at Dec. 31, 2017 $ 854 455,401 (17,867) (3,774) (231,630) 202,984
Balance at the beginning of the period (in shares) at Dec. 31, 2017 562,119,334          
Increase (Decrease) in Stockholders' Equity            
Net loss         (59,341) (59,341)
Issuance of shares upon exercise of stock options $ 7 2,926       2,933
Issuance of shares upon exercise of stock options (in shares) 5,102,742          
Issuance of shares upon completion of registered direct offering $ 78 99,575       99,653
Issuance of shares upon completion of registered direct offering (in shares) 60,000,000          
Other comprehensive loss before reclassifications            
Foreign currency translation adjustments     5,103     5,103
Unrealized holding gains on available-for-sale debt securities, net of tax of $0       1,252   1,252
Reclassification from accumulated other comprehensive loss of losses on available-for-sale debt securities included in net loss, net of tax of $0       (2,473)   (2,473)
Share-based compensation expense   12,453       12,453
Balance at the end of the period at Sep. 30, 2018 $ 939 $ 570,355 $ (12,764) $ (49) $ (282,326) $ 276,155
Balance at the end of the period (in shares) at Sep. 30, 2018 627,222,076