Annual report pursuant to Section 13 and 15(d)

Income taxes - Reconciliation of Effective Tax Rate (Details)

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Income taxes - Reconciliation of Effective Tax Rate (Details) - Her Majesty's Revenue and Customs (HMRC)
12 Months Ended
Apr. 01, 2017
Dec. 31, 2019
Dec. 31, 2018
Income taxes      
UK tax rate 19.00% 19.00% 19.00%
Reimbursable tax credits within Research and development expense   2.80% 3.50%
R&D expenditures surrendered for R&D tax credit refund   (7.70%) (10.00%)
Permanent differences for unrealized foreign exchange subsidiaryon intercompany loans of a long-term investment nature   (1.50%)  
Change in valuation allowances   (12.40%) (17.50%)
Difference in tax rates   (1.20%) (1.30%)
R&D tax credits generated   1.50% 5.10%
Other   (0.70%) 0.80%
Effective income tax rate   (0.20%) (0.50%)