Quarterly report pursuant to Section 13 or 15(d)

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CHANGE IN EQUITY

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UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CHANGE IN EQUITY - USD ($)
$ in Thousands
Common stock
Additional paid in capital
Accumulated other comprehensive (loss) income
Accumulated deficit
Total
Balance at the beginning of the period, shares at Dec. 31, 2020 928,754,958        
Balance at the beginning of the period at Dec. 31, 2020 $ 1,325 $ 935,706 $ (10,048) $ (585,756) $ 341,227
Increase (Decrease) in Stockholders' Equity          
Issuance of shares upon exercise of stock options $ 6 529     535
Issuance of shares upon exercise of stock options (in shares) 4,062,210        
Other comprehensive loss     (176)   (176)
Share-based compensation expense   5,334     5,334
Net loss       (37,763) (37,763)
Balance at the end of the period at Mar. 31, 2021 $ 1,331 941,569 (10,224) (623,519) $ 309,157
Balance at the end of the period, shares at Mar. 31, 2021 932,817,168        
Balance at the beginning of the period, shares at Dec. 31, 2021 937,547,934       937,547,934
Balance at the beginning of the period at Dec. 31, 2021 $ 1,337 959,611 (11,142) (743,846) $ 205,960
Increase (Decrease) in Stockholders' Equity          
Issuance of shares upon exercise of stock options $ 5 30     35
Issuance of shares upon exercise of stock options (in shares) 3,318,072        
Other comprehensive loss     1,829   1,829
Share-based compensation expense   5,586     5,586
Net loss       (50,265) (50,265)
Balance at the end of the period at Mar. 31, 2022 $ 1,342 $ 965,227 $ (9,313) $ (794,111) $ 163,145
Balance at the end of the period, shares at Mar. 31, 2022 940,866,006       940,866,006