Quarterly report pursuant to Section 13 or 15(d)

Accrued expenses and other current liabilities (Details)

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Accrued expenses and other current liabilities (Details) - USD ($)
$ in Thousands
Mar. 31, 2018
Dec. 31, 2017
Accrued expenses and other current liabilities    
Accrued clinical and development expenditure $ 10,212 $ 10,065
Accrued employee expenses 4,084 6,592
VAT 458 5,741
Other accrued expenditure 3,829 3,944
Accrued capital expenditure 585 502
Other liabilities 482 357
Total $ 19,650 $ 27,201