Quarterly report pursuant to Section 13 or 15(d)

Contingencies and commitments - Universal Cells Research, Collaboration and License Agreement and Co-development and Co-commercialization agreement (Details)

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Contingencies and commitments - Universal Cells Research, Collaboration and License Agreement and Co-development and Co-commercialization agreement (Details) - Collaboration and license agreement - Universal Cells, Inc. - USD ($)
 1 Months Ended 12 Months Ended
Feb. 29, 2016
Nov. 30, 2015
Dec. 31, 2018
Dec. 31, 2017
Jun. 30, 2022
Contingencies and commitments          
Upfront license and start-up fees   $ 2,500,000      
Milestone payments $ 3,000,000   $ 200,000 $ 900,000  
Maximum          
Contingencies and commitments          
Potential milestone payments         $ 37,600,000
Milestone payments one accrued but not yet paid         800,000
Milestone payments two accrued but not yet paid         600,000
Milestone payments three accrued but not yet paid         2,000,000
Milestone payment invoiced but not paid         $ 500,000