Annual report pursuant to Section 13 and 15(d)

Revenue - Collaboration Agreement - The Genentech Collaboration and License Agreement (Details)

v3.24.0.1
Revenue - Collaboration Agreement - The Genentech Collaboration and License Agreement (Details)
3 Months Ended 12 Months Ended
Sep. 03, 2021
USD ($)
item
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2023
USD ($)
Revenue          
Number of additional terms | item 2        
Collaboration target basis days 180 days        
Number of days without HSR clearance after effective date before termination 180 days        
Strategic Collaboration and License Agreement          
Revenue          
Number of types of therapies to be co-developed | item 2        
Initial period of collaborated research 8 years        
Number of additional terms | item 2        
Number of additional years 2 years        
Number of years additional payments are due 5 years        
Upfront payment received       $ 150,000,000  
Milestone payments   $ 15,000,000 $ 20,000,000    
Amount of additional payments receivable under the research program $ 150,000,000        
Total Number off the Shelf Collaboration Targets | item 5        
Aggregate amount of the transaction price that is allocated to performance obligations that are unsatisfied or partially satisfied under the agreements   275,185,000     $ 275,185,000
Amount of transaction price of the agreement at inception   313,600,000     313,600,000
Collaboration Agreement Research Service and Rights, Upfront Payment Earned         150,000,000
Collaboration Agreement Research Service and Rights, Additional Payment Earned         150,000,000
Collaboration Agreement Research Service and Rights, Other Consideration         13,600,000
Strategic Collaboration and License Agreement | Research Service Rights Granted for Initial Off the Shelf Collaboration Targets          
Revenue          
Aggregate amount of the transaction price that is allocated to performance obligations that are unsatisfied or partially satisfied under the agreements   168,349,000     168,349,000
Strategic Collaboration and License Agreement | Research Service Rights Granted for Personalized Therapies          
Revenue          
Aggregate amount of the transaction price that is allocated to performance obligations that are unsatisfied or partially satisfied under the agreements   87,359,000     87,359,000
Strategic Collaboration and License Agreement | Material Right to Designate the Additional Off the Shelf Collaboration Target          
Revenue          
Aggregate amount of the transaction price that is allocated to performance obligations that are unsatisfied or partially satisfied under the agreements   13,147,000     13,147,000
Strategic Collaboration and License Agreement | Material Right for First Option Extend the Research Term          
Revenue          
Aggregate amount of the transaction price that is allocated to performance obligations that are unsatisfied or partially satisfied under the agreements   5,064,000     5,064,000
Strategic Collaboration and License Agreement | Material Right for Second Option Extend the Research Term          
Revenue          
Aggregate amount of the transaction price that is allocated to performance obligations that are unsatisfied or partially satisfied under the agreements   $ 1,266,000     $ 1,266,000
Development Milestone | Strategic Collaboration and License Agreement | Maximum          
Revenue          
Milestone payments $ 200,000,000        
Development Milestone - Off The Shelf Member T-cell Therapies | Strategic Collaboration and License Agreement | Maximum          
Revenue          
Milestone payments 100,000,000        
Research Milestone | Strategic Collaboration and License Agreement | Maximum          
Revenue          
Milestone payments $ 50,000,000        
Commercialisation Milestone | Strategic Collaboration and License Agreement          
Revenue          
Total Number off the Shelf Collaboration Targets | item 5        
Commercialisation Milestone | Strategic Collaboration and License Agreement | Maximum          
Revenue          
Milestone payments $ 1,100,000,000        
Sales Milestone | Strategic Collaboration and License Agreement          
Revenue          
Number of co-development targets | item 5        
Sales Milestone | Strategic Collaboration and License Agreement | Maximum          
Revenue          
Milestone payments $ 1,500,000,000        
Regulatory, Sales, And Royalties Milestones | Strategic Collaboration and License Agreement          
Revenue          
Percentage of profit (loss) sharing ratio 50.00%        
Regulatory, Sales, And Royalties Milestones | Strategic Collaboration and License Agreement | Maximum          
Revenue          
Milestone payments $ 800,000,000