Quarterly report pursuant to Section 13 or 15(d)

Share-based compensation - Share-based Compensation Expense (Details)

v3.7.0.1
Share-based compensation - Share-based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense $ 2,072 $ 2,439 $ 4,757 $ 4,541
Research and development        
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense 871 1,376 2,229 2,268
General and administrative        
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense $ 1,201 $ 1,063 $ 2,528 $ 2,273