Quarterly report pursuant to Section 13 or 15(d)

Accrued expenses and other current liabilities (Details)

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Accrued expenses and other current liabilities (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2017
Dec. 31, 2016
Accrued expenses and other current liabilities    
Accrued liabilities for clinical and development expenses $ 5,373 $ 4,938
Accrued employee compensation and benefits payable 2,767 4,539
Accrued capital expenditure 4,190 3,954
Value added tax (VAT)   2,014
Other accrued purchases 1,498 1,003
Other current liabilities 1,282 1,080
Total 15,110 $ 17,528
Milestone payments $ 0