Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY

v3.20.4
CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY - USD ($)
$ in Thousands
Common stock
January Offering
Common stock
June Offering
Common stock
Over Allotment January
Common stock
Over Allotment June
Common stock
Cumulative Effect, Period of Adoption, Adjusted Balance [Member]
Common stock
Additional paid in capital
January Offering
Additional paid in capital
June Offering
Additional paid in capital
Over Allotment January
Additional paid in capital
Over Allotment June
Additional paid in capital
Cumulative Effect, Period of Adoption, Adjusted Balance [Member]
Additional paid in capital
Accumulated other comprehensive (loss) income
Cumulative Effect, Period of Adoption, Adjusted Balance [Member]
Accumulated other comprehensive (loss) income
Accumulated deficit
Cumulative Effect, Period of Adoption, Adjustment [Member]
Accumulated deficit
Cumulative Effect, Period of Adoption, Adjusted Balance [Member]
Accumulated deficit
January Offering
June Offering
Over Allotment January
Over Allotment June
Cumulative Effect, Period of Adoption, Adjustment [Member]
Cumulative Effect, Period of Adoption, Adjusted Balance [Member]
Total
Increase (Decrease) in Stockholders' Equity                                                
Beginning balance as adjusted, shares         562,119,334                                      
Balance at the beginning of the period, shares at Dec. 31, 2017           562,119,334                                    
Balance at the beginning of the period at Dec. 31, 2017         $ 854 $ 854         $ 455,401 $ 455,401 $ (21,641) $ (21,641) $ 8,645 $ (222,985) $ (231,630)         $ 8,645 $ 211,629 $ 202,984
Increase (Decrease) in Stockholders' Equity                                                
Issuance of shares upon exercise of stock options           $ 7           3,030                       $ 3,037
Issuance of shares upon exercise of stock options (in shares)           5,334,936                                   5,334,936
Issuance of shares upon completion of public offering, net of issuance costs           $ 78           99,575                       $ 99,653
Issuance of shares upon completion of public offering, net of issuance costs (in shares)           60,000,000                                    
Other comprehensive income (loss)                           11,878                   11,878
Share-based compensation expense                       16,202                       16,202
Net loss                                 (95,514)             (95,514)
Balance at the end of the period at Dec. 31, 2018           $ 939           574,208   (9,763)     (318,499)             246,885
Balance at the end of the period, shares at Dec. 31, 2018           627,454,270                                    
Increase (Decrease) in Stockholders' Equity                                                
Issuance of shares upon exercise of stock options           $ 4           362                       $ 366
Issuance of shares upon exercise of stock options (in shares)           3,549,298                                   3,549,298
Other comprehensive income (loss)                           2,499                   $ 2,499
Share-based compensation expense                       11,053                       11,053
Net loss                                 (137,165)             (137,165)
Balance at the end of the period at Dec. 31, 2019           $ 943           585,623   (7,264)     (455,664)             $ 123,638
Balance at the end of the period, shares at Dec. 31, 2019           631,003,568                                   631,003,568
Increase (Decrease) in Stockholders' Equity                                                
Issuance of shares upon exercise of stock options           $ 14           5,649                       $ 5,663
Issuance of shares upon exercise of stock options (in shares)           11,401,390                                   11,401,390
Issuance of shares upon completion of public offering, net of issuance costs $ 165 $ 155 $ 24 $ 24     $ 78,451 $ 209,831 $ 11,914 $ 33,824               $ 78,616 $ 209,986 $ 11,938 $ 33,848      
Issuance of shares upon completion of public offering, net of issuance costs (in shares) 126,000,000 123,000,000 18,900,000 18,450,000                                        
Other comprehensive income (loss)                           (2,784)                   $ (2,784)
Share-based compensation expense                       10,414                       10,414
Net loss                                 (130,092)             (130,092)
Balance at the end of the period at Dec. 31, 2020           $ 1,325           $ 935,706   $ (10,048)     $ (585,756)             $ 341,227
Balance at the end of the period, shares at Dec. 31, 2020           928,754,958                                   928,754,958