Annual report pursuant to Section 13 and 15(d)

Share-based compensation - Share-based Compensation Expense (Details)

v3.20.4
Share-based compensation - Share-based Compensation Expense (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Total share-based compensation expense included in the consolidated statements of operations      
Total share-based compensation expense $ 10,414 $ 11,053 $ 16,202
Research and development      
Total share-based compensation expense included in the consolidated statements of operations      
Total share-based compensation expense 4,417 3,812 8,340
General and administrative      
Total share-based compensation expense included in the consolidated statements of operations      
Total share-based compensation expense $ 5,997 $ 7,241 $ 7,862