Annual report [Section 13 and 15(d), not S-K Item 405]

Revenue - Revenue from contracts with customers (Details)

v3.25.1
Revenue - Revenue from contracts with customers (Details)
1 Months Ended 3 Months Ended 12 Months Ended
Nov. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
$ / £
Sep. 30, 2023
USD ($)
Jun. 30, 2023
USD ($)
Dec. 31, 2024
USD ($)
$ / £
Dec. 31, 2023
USD ($)
$ / £
Dec. 31, 2022
USD ($)
$ / £
Revenue              
Revenue         $ 178,032,000 $ 60,281,000 $ 27,148,000
Deferred revenue decrease           69,922,000 6,379,000
Deferred revenue   $ 178,033,000     108,111,000 178,033,000 $ 184,412,000
Revenue recognized in the period         163,353,000 59,072,000  
Amount of increase in deferred income caused by the change in the exchange rate         $ 1,600,000 $ 7,174,000  
Exchange rate | $ / £   1.27     1.25 1.27 1.21
Product revenue, net              
Revenue              
Revenue         $ 1,236,000    
Development revenue              
Revenue              
Revenue         176,796,000 $ 60,281,000 $ 27,148,000
Galapagos Collaboration and Exclusive License Agreement              
Revenue              
Milestone payments received $ 15,000,000       85,000,000    
GSK Collaboration And License Agreement              
Revenue              
Milestone payments received   $ 15,226,000 $ 3,727,000 $ 9,613,000 9,673,000    
Genentech              
Revenue              
Milestone payments received         876,000    
Aggregate amount of the transaction price that is allocated to performance obligations         $ 124,393,000