Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED BALANCE SHEETS

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CONSOLIDATED BALANCE SHEETS - USD ($)
Dec. 31, 2022
Dec. 31, 2021
Current assets    
Cash and cash equivalents $ 108,033,000 $ 149,948,000
Marketable securities - available-for-sale debt securities 96,572,000 219,632,000
Accounts receivable, net of allowance for doubtful accounts of $0 and $0 7,435,000 752,000
Other current assets and prepaid expenses 43,330,000 45,126,000
Total current assets 255,370,000 415,458,000
Restricted cash 1,569,000 1,718,000
Operating lease right-of-use assets, net of accumulated amortization of $9,470 and $7,253 18,019,000 20,875,000
Property, plant and equipment, net of accumulated depreciation of $38,588 and $36,253 53,516,000 30,494,000
Intangible assets, net of accumulated amortization of $4,676 and $4,051 442,000 1,000,000
Total assets 328,916,000 469,545,000
Current liabilities    
Accounts payable 4,753,000 8,113,000
Operating lease liabilities, current 2,728,000 2,320,000
Accrued expenses and other current liabilities 31,215,000 29,909,000
Restructuring provision 2,285,000  
Deferred revenue, current 23,520,000 22,199,000
Total current liabilities 64,501,000 62,541,000
Operating lease liabilities, non-current 20,349,000 23,148,000
Deferred revenue, non-current 160,892,000 177,223,000
Other liabilities, non-current 1,296,000 673,000
Total liabilities 247,038,000 263,585,000
Stockholders' equity    
Common stock - Ordinary shares par value £0.001, 1,282,773,750 authorized and 982,719,936 issued and outstanding (2021: 1,240,853,520 authorized and 937,547,934 issued and outstanding) 1,399,000 1,337,000
Additional paid in capital 990,656,000 959,611,000
Accumulated other comprehensive loss (875,000) (11,142,000)
Accumulated deficit (909,302,000) (743,846,000)
Total stockholders' equity 81,878,000 205,960,000
Total liabilities and stockholders' equity $ 328,916,000 $ 469,545,000