Annual report pursuant to Section 13 and 15(d)

Share-based compensation - Share-based Compensation Expense (Details)

v3.22.4
Share-based compensation - Share-based Compensation Expense (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Total share-based compensation expense included in the consolidated statements of operations      
Total share-based compensation expense $ 18,240 $ 20,629 $ 10,414
Research and development      
Total share-based compensation expense included in the consolidated statements of operations      
Total share-based compensation expense 6,264 9,052 4,417
General and administrative      
Total share-based compensation expense included in the consolidated statements of operations      
Total share-based compensation expense $ 11,976 $ 11,577 $ 5,997